New USPlus PRO shown in new study to significantly improve men’s urinary performance, bladder control and sexual function.
-- Valensa International has introduced a new clinically proven men’s health ingredient, USPlus PRO which launches with a newly published study in Food and Nutrition demonstrating a “three-in-one” benefit profile for men focusing on their unmet needs. More than half of men over 50 experience lower urinary tract symptoms (LUTS) including frequent urination, incomplete bladder emptying, and weak urinary flow. As men age, these symptoms often worsen and can progress to more distressing issues such as urinary incontinence and sensual dysfunction. Despite the large and growing need, current natural solutions and therapeutic options still leave many consumers dissatisfied due to limited effectiveness or concerns about unwanted side effects. This need gap can be addressed now by USPlus PRO.
USPlus PRO is the only three-in-one clinically proven natural ingredient for men’s urinary performance, bladder control, and sexual function. According to Dr. Leigh Vinocur, one of the study’s authors, “no other natural ingredient has performed well across all three benefits areas in a double blind placebo controlled clinical trial.”
The study compared supplementation with USPlus PRO and placebo in men aged 45 to 80 with mostly moderate to severe (LUTS). The participants were randomized 1:1 to USPlus PRO (providing 240 mg proprietary free fatty acids) or placebo for 12 weeks.
In as early as four weeks, a clinically meaningful relief in symptom was evident by the reduction in International Prostate Symptom Score (IPSS). At week 12, statistically significant results and positive outcomes were observed in the USPlus PRO group for the IPSS score, voiding sub score (IPSS-V), incomplete emptying, weak stream, Brief Sexual Function Inventory (BSFI) total scores, and erection domain scores. The outcomes further validated the safety of USPlus PRO.
The authors concluded that men who supplemented with USPlus PRO for 12 weeks had 50% reduction in frequency of weak stream, 60% reduction in straining during urination, fewer nighttime bathroom trips and twice more satisfaction in bladder emptying compared to baseline before using USPlus PRO. In addition, significant improvements in sexual function were reported by men using USPlus PRO in as early as four weeks. There was a 3.5 times improvement in sexual function in men 50-plus compared to placebo.
According to Dr. Amanda Rao, Principal Investigator at RDC Clinical, who conducted the study, “The improvements observed in urinary symptoms and sexual function were substantial. USPlus PRO demonstrated a 6.4-point reduction in IPSS, a statistically significant change compared to placebo." She added that 80% of participants achieved a clinically meaningful reduction in IPSS, with 90% of those with severe symptoms experiencing clinically significant improvement.
USPlus Pro is a patented Free Fatty Acid extract from Serenoa repens. By enriching the free fatty acids most responsible for the regulation of the 5AR-2 enzyme to inhibit the conversion of testosterone to DHT and supporting multi-mechanistic beneficial pathways, USPlus PRO delivers greater impact in one small daily dose of just 240 mg free fatty acids allowing for more formulation flexibility. According to Uma Palaniswamy, Chief Executive Officer and President of Valensa International “USPlus PRO’s clinical outcomes and proven benefits offers brands the opportunity to move beyond just prostate health to a broader men’s health territory by providing fast acting relief and experiential benefits within a month. USPlus PRO delivered two times greater improvement in performance and three times faster urinary symptom relief than other natural ingredients (cranberry, saw palmetto and added beta-sitosterol).”
About Valensa
Valensa International’s commitment to safety, quality and the environment is represented by the US Pharmacopeia Dietary Ingredient Verification Program, FDA Good Manufacturing Practice compliance and sustainability practices. Headquartered in central Florida near a protected saw palmetto grove, Valensa International is a leading innovator and next-generation supplier of pure, science-based, clinically effective nutraceutical ingredients proven to benefit health and wellness. For over 25 years, Valensa has partnered with nutraceutical, cosmeceutical, food, and pharmaceutical companies to bring condition-specific results to market for human and companion animal well-being.
Valensa is a fully integrated manufacturer of Serevelle 3-in-1 hair ingredient for women and men, USPlus PRO for Men’s Urinary Performance, USPlus lipidosterolic extract of saw palmetto (USP Verified), Zanthin Natural Astaxanthin, FlexProMD Joint health platform, Parry Organic Spirulina & Chlorella. Valensa’s ingredients are available in multiple forms and suitable for versatile applications including softgels, capsules, tablets, gummies, powder blends and liposomal emulsions.
More information is available at valensa.com.
Reference:
Rao A. et al. “Efficacy and Safety of a Proprietary Free Fatty Acid Rich Saw Palmetto Extract (USPlus PRO) for Lower Urinary Tract Symptoms in Males: A Randomized, Double-Blind, Placebo-Controlled Trial” Food and Nutrition Sciences 2026 March Vol. 17, No. 3
Contact Info:
Name: Adam Bushey
Email: Send Email
Organization: Valensa International
Phone: 877-876-8872
Website: https://valensa.com/
Release ID: 89186972
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