Ancient fermented soybean enzyme from the world's longest-living population now available to support cardiovascular health globally
WILMINGTON, DE / ACCESS Newswire / June 10, 2025 / 8 Months ago, Natural Foundation Supplements launched Nattokinase, a premium Nattokinase supplement that harnesses a key component of the Japanese diet-a population renowned for maintaining the world's second highest life expectancy at 84.8 years. This groundbreaking supplement brings the cardiovascular benefits of natto, a traditional fermented soybean dish consumed daily by millions of Japanese, to health-conscious consumers worldwide.
The Longevity Connection
Japan's exceptional longevity statistics have long fascinated researchers studying the secrets of healthy aging. With Japanese women living an average of 87.1 years and men 81.5 years, scientists have intensively studied the Japanese lifestyle and diet to understand this remarkable health advantage. Among the unique dietary components consistently linked to Japanese longevity is natto-and specifically its powerful enzyme, nattokinase.
"When you look at populations with extraordinary longevity, you inevitably find dietary secrets that the rest of the world can learn from," said Logan King, CEO at Natural Foundation Supplements. "Nattokinase represents one of Japan's most intriguing longevity factors-an enzyme that's been consumed safely for over 1,000 years by the world's longest-living people."
Combine this with scientific evidence, and things get really interesting..
Research Highlights
A 12-Month Study On Artery Plaque
In a landmark 2020 study involving over 1,000 participants, daily supplementation with nattokinase resulted in a 36% reduction in arterial plaque thickness over 12 months. Other research shows nattokinase may help support healthy blood pressure levels, improve circulation, and even reduce blood clot formation by naturally breaking down fibrin, a protein that contributes to clots and arterial stiffness.
Hsieh MC, et al. "Clinical Evaluation of Nattokinase Dietary Supplementation for Carotid Artery Atherosclerosis." Scientific Reports. 2022;12:12913.
DOI: 10.1038/s41598-022-17155-z
16-Year Study on Heart Attack & Stroke Risk
A large-scale prospective study conducted over 16 years in Japan followed 29,132 participants and found that higher consumption of nattō (rich in nattokinase) was associated with a 25% lower risk of heart attack and a 33% lower risk of stroke in men. The study emphasized the role of nattō-derived enzymes in reducing cardiovascular events.
Kurahashi N, et al. "Soy product and isoflavone intake in relation to cardiovascular disease mortality in Japan." Am J Clin Nutr. 2008;87(1):206-12.
PubMed ID: 18175749
Nattokinase & Blood Pressure
In a randomized, double-blind, placebo-controlled trial, 79 adults with untreated prehypertension or stage 1 hypertension took 2,000 FU of nattokinase daily for 8 weeks. The nattokinase group experienced a significant reduction in both systolic (-5.55 mmHg) and diastolic (-2.84 mmHg) blood pressure compared to placebo.
Kim JY, et al. "Nattokinase decreases blood pressure in patients with hypertension." Hypertens Res. 2008 Jun;31(8):1583-8.
PubMed ID: 18784664
Blood Clots in Flight Passengers
In a placebo-controlled trial, 204 airline passengers on long-haul flights took a supplement containing nattokinase and pycnogenol. Those in the treatment group had significantly fewer instances of deep vein thrombosis (DVT) and less leg swelling, suggesting strong circulation support.
Cesarone MR, et al. "Prevention of DVT in long-haul flights with Pycnogenol and nattokinase." Angiology. 2008 May-Jun;59(3):301-6.
PubMed ID: 18596410
About Our Nattokinase Supplement
Natural Foundation Supplements' Nattokinase has quickly become one of our most in-demand products, with over 20,000 bottles sold worldwide and growing traction across the UK, US, and Europe. Why? Because more people are waking up to the power of natural solutions for heart health.
Derived from the traditional Japanese superfood natto, our Nattokinase supplement offers a science-backed, natural way to support healthy circulation, manage blood pressure, and reduce the risk of arterial plaque buildup - without synthetic drugs or harsh side effects.
As studies continue to highlight its effectiveness, customers are turning to Nattokinase as a proactive daily tool for maintaining cardiovascular health. With every batch third-party tested for purity and potency, we're committed to delivering the highest quality - so you can support your heart, naturally.
Quality You Can Trust
Natural Foundation's Nattokinase is:
Sourced from non-GMO fermented soybeans.
Standardised to 5,000 FU per capsule.
Third-party tested for purity and potency.
Growing Market Recognition
The global nattokinase market has experienced significant growth as consumers increasingly seek natural alternatives for cardiovascular support. Healthcare practitioners are taking notice of the mounting research, with many incorporating nattokinase into their recommendations for patients focused on heart health maintenance.
Now Available
Natural Foundation's Nattokinase supplement is available now at https://nfsupplements.com/products/nattokinase
and selected retailers. For more information, visit the website or contact info@nfsupplements.co.uk
As with all supplements, consumers should consult with healthcare providers before use, particularly those taking blood-thinning medications or with bleeding disorders.
This press release contains statements about the potential benefits of nattokinase based on published research. These statements have not been evaluated by the FDA and are not intended to diagnose, treat, cure, or prevent any disease.
SOURCE: Nattokinase
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