FORM 4 Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP OF SECURITIES Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934, Section 17(a) of the Public Utility Holding Company Act of 1935 or Section 30(h) of the Investment Company Act of 1940

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1. Name and Address of Reporting Person * Pigman Karen C   2. Issuer Name and Ticker or Trading Symbol OLD DOMINION FREIGHT LINE INC/VA [ODFL] 5. Relationship of Reporting Person(s) to Issuer (Check all applicable) _____ Director __X__ 10% Owner _____ Officer (give title below) __X__ Other (specify below) Member of Section 13(d) group (Last) (First) (Middle) 65 BEACH ROAD SOUTH 3. Date of Earliest Transaction (Month/Day/Year) 10/27/2010 (Street) WILMINGTON, NC 28411 4. If Amendment, Date Original Filed(Month/Day/Year) 6. Individual or Joint/Group Filing(Check Applicable Line) ___ Form filed by One Reporting Person _X_ Form filed by More than One Reporting Person (City) (State) (Zip) Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned

1.Title of Security (Instr. 3) 2. Transaction Date (Month/Day/Year) 2A. Deemed Execution Date, if any (Month/Day/Year) 3. Transaction Code (Instr. 8) 4. Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5) 5. Amount of Securities Beneficially Owned Following Reported Transaction(s) (Instr. 3 and 4) 6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 7. Nature of Indirect Beneficial Ownership (Instr. 4) Code V Amount (A) or (D) Price Common Stock 10/27/2010   S(1)   11,699 D $ 28 658,261 (2) I As trustee of the Karen C. Pigman Revocable Trust Common Stock 10/27/2010   S(1)   2,805 D $ 28 127,797 (3) I As trustee of the Melissa A. Penley Revocable Trust Common Stock 10/27/2010   S(1)   2,805 D $ 28 127,797 (4) I As trustee of the Matthew A. Penley Revocable Trust Common Stock 10/27/2010   S(1)   2,805 D $ 28 127,797 (5) I As trustee of the Mark A. Penley Revocable Trust Common Stock               75,798 (2) I By Karen C. Pigman Irrevocable Trust Number One (Audrey L. Congdon, Trustee) Common Stock               58,198 (2) I As trustee of an Irrevocable Trust Agreement dated 12/18/98 fbo Melissa Penley Common Stock               58,198 (2) I As trustee of an Irrevocable Trust Agreement dated 12/18/98 fbo Matthew Penley Common Stock               58,198 (2) I As trustee of an Irrevocable Trust Agreement dated 12/18/98 fbo Mark Penley Common Stock               163,626 (2) I By Karen C. Pigman February 2009 Grantor Retained Annuity Trust (Audrey L. Congdon, Trustee) Common Stock               430,651 (2) I As co-trustee of the Earl E. Congdon GRAT Remainder Trust Common Stock 10/28/2010   S(1)   11,180 D $ 28.009 (6) 647,081 (2) I As trustee of the Karen C. Pigman Revocable Trust Common Stock 10/28/2010   S(1)   2,685 D $ 28.009 (6) 125,112 (3) I As trustee of the Melissa A. Penley Revocable Trust Common Stock 10/28/2010   S(1)   2,685 D $ 28.009 (6) 125,112 (4) I As trustee of the Matthew A. Penley Revocable Trust Common Stock 10/28/2010   S(1)   2,685 D $ 28.009 (6) 125,112 (5) I As trustee of the Mark A. Penley Revocable Trust

Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
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Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned
(e.g., puts, calls, warrants, options, convertible securities)

1. Title of Derivative Security (Instr. 3)

2. Conversion or Exercise Price of Derivative Security

3. Transaction Date (Month/Day/Year)

3A. Deemed Execution Date, if any (Month/Day/Year)

4. Transaction Code (Instr. 8)

5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4, and 5)

6. Date Exercisable and Expiration Date (Month/Day/Year)

7. Title and Amount of Underlying Securities (Instr. 3 and 4)

8. Price of Derivative Security (Instr. 5)

9. Number of Derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4)

10. Ownership Form of Derivative Security: Direct (D) or Indirect (I) (Instr. 4)

11. Nature of Indirect Beneficial Ownership (Instr. 4)

Code

V

(A)

(D)

Date Exercisable

Expiration Date

Title

Amount or Number of Shares

Reporting Owners

Reporting Owner Name / Address	Relationships
	Director	10% Owner	Officer	Other
Pigman Karen C 65 BEACH ROAD SOUTH WILMINGTON, NC 28411		X		Member of Section 13(d) group
Penley Melissa A. 65 BEACH ROAD SOUTH WILMINGTON, NC 28411		X		Member of Section 13(d) group
Penley Mark A 65 BEACH ROAD SOUTH WILMINGTON, NC 28411		X		Member of Section 13(d) group
Penley Matthew A. 3608 ROY MESSER HIGHWAY WHITE PINE, TN 37890		X		Member of Sectin 13(d) group

Signatures

/s/ Joel B. McCarty, Jr., by Power of Attorney		10/29/2010
**Signature of Reporting Person		Date
/s/ Joel B. McCarty, Jr., by Power of Attorney		10/29/2010
**Signature of Reporting Person		Date
/s/ Joel B. McCarty, Jr., by Power of Attorney		10/29/2010
**Signature of Reporting Person		Date
/s/ Joel B. McCarty, Jr., by Power of Attorney		10/29/2010
**Signature of Reporting Person		Date

Explanation of Responses:

*	If the form is filed by more than one reporting person, see Instruction 4(b)(v).
**	Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
(1)	The sales reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on August 30, 2010.
(2)	These securities are beneficially owned by Karen C. Pigman, who may be deemed a member of a "group" for purposes of Section 13(d) of the Exchange Act. The other members of the Section 13(d) group are indentified in a Schedule 13D filed with the Securities and Exchange Commission on September 9, 2010.
(3)	These securities are beneficially owned by Melissa A. Penley, who may be deemed a member of a "group" for purposes of Section 13(d) of the Exchange Act. The other members of the Section 13(d) group are indentified in a Schedule 13D filed with the Securities and Exchange Commission on September 9, 2010.
(4)	These securities are beneficially owned by Matthew A. Penley, who may be deemed a member of a "group" for purposes of Section 13(d) of the Exchange Act. The other members of the Section 13(d) group are indentified in a Schedule 13D filed with the Securities and Exchange Commission on September 9, 2010.
(5)	These securities are beneficially owned by Mark A. Penley, who may be deemed a member of a "group" for purposes of Section 13(d) of the Exchange Act. The other members of the Section 13(d) group are indentified in a Schedule 13D filed with the Securities and Exchange Commission on September 9, 2010.
(6)	The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $28.00 to $28.015, inclusive. The reporting person undertakes to provide to the issuer, any security holder of the issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

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