Filed by Boston Scientific Corporation

Pursuant to Rule 425 under the Securities Act of 1933

and deemed filed pursuant to Rule 14a-6

under the Securities Exchange Act of 1934

Subject Company: Guidant Corporation

Commission File No.: 333-131608

The following material relates to a presentation given by Boston Scientific's Chief Financial Officer at the SG Cowen & Co. 26^th Annual Health Care Conference and made available on Boston Scientific's website.

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[LOGO]

[LOGO]

Creating a Global Medical Device Leader

Safe Harbor: Forward-Looking Statements

This presentation contains “forward-looking statements,” including, among other statements, statements regarding the proposed business combination between Boston Scientific Corporation and Guidant Corporation, and the anticipated consequences and benefits of such transaction. Statements made in the future tense, and words such as “anticipate”, “expect”, “project”, “believe”, “plan”, “estimate”, “intend”, “will”, “may” and similar expressions are intended to identify forward-looking statements. These statements are based on current expectations, but are subject to certain risks and uncertainties, many of which are difficult to predict and are beyond the control of Boston Scientific or Guidant. Relevant risks and uncertainties include those referenced in Boston Scientific’s and Guidant’s filings with the Securities and Exchange Commission (“SEC”) (which can be obtained as described in “Additional Information” below), and include: general industry conditions and competition; economic conditions, such as interest rate and currency exchange rate fluctuations; technological advances and patents attained by competitors; challenges inherent in new product development, including obtaining regulatory approvals; domestic and foreign health care reforms and governmental laws and regulations; and trends toward health care cost containment. Risks and uncertainties relating to the proposed transaction include: required regulatory approvals will not be obtained in a timely manner, if at all; the proposed transaction will not be consummated; the anticipated benefits of the proposed transaction will not be realized; and the integration of Guidant’s operations with Boston Scientific will be materially delayed or will be more costly or difficult than expected. These risks and uncertainties could cause actual results to differ materially from those expressed in or implied by the forward-looking statements, and therefore should be carefully considered. Neither Boston Scientific nor Guidant assumes any obligation to update any forward-looking statements as a result of new information or future events or developments.

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Safe Harbor: Additional Information

Boston Scientific and Guidant have filed a definitive prospectus/joint proxy statement with the SEC in connection with the proposed transaction. The material contained herein is not a substitute for the definitive prospectus/joint proxy statement or any other documents that Boston Scientific and Guidant have filed or will file with the SEC. Investors and security holders are urged to read the definitive prospectus/joint proxy statement and any other relevant documents filed or to be filed by Boston Scientific or Guidant, because they contain or will contain important information about the proposed transaction. The definitive prospectus/joint proxy statement is, and other documents filed or to be filed by Boston Scientific and Guidant with the SEC are or will be, available free of charge at the SEC’s website (www.sec.gov) or from Boston Scientific by directing a request to Boston Scientific Corporation, One Boston Scientific Place, Natick, Massachusetts 01760-1537, Attention: Milan Kofol, Investor Relations, or from Guidant by directing a request to Guidant Corporation, 111 Monument Circle, 29th Floor, Indianapolis, Indiana 46204, Attention: Investor Relations.

Boston Scientific, Guidant and their respective directors, executive officers and other employees may be deemed to be participants in the solicitation of proxies from the security holders of Boston Scientific or Guidant in connection with the proposed transaction. Information about Boston Scientific’s directors and executive officers is available in Boston Scientific’s Annual Report on Form 10-K for the year ended December 31, 2005, and information about Guidant’s directors and executive officers is available in Guidant’s Annual Report on Form 10-K for the year ended December 31, 2005. Additional information about the interests of potential participants is included in the definitive prospectus/joint proxy statement referred to above.

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[LOGO]

[CHART]

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Strategic Build To Date

90%+ of sales from market leading products…

[CHART]

2005 Actual Sales

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Breadth and Depth of Technology

$6.3B of Technologies…

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Worldwide Market Leadership

Source: 2005 & 2004, respectively, company results, analyst reports, MRG reporting
Includes vascular sealing and embolic protection

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Financial Results

(Excluding special charges)

[CHART]

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Interventional Cardiovascular Market Today

Interventional Cardiovascular Market
Before BSC-GDT Combination

[CHART]

Source:  Wall Street Research.

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DES Market Positions
Competitive Markets (excludes Japan)

[CHART]

Industry sources

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DES Market Outlook
Wall Street Estimates

[CHART]

Source: Wall Street Research.

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Guidant:  The Transforming Event

Cardiovascular Market
Before BSC-GDT Combination

[CHART]

Source:  Wall Street Research.

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Achieving Enhanced Diversification and Higher Growth

Preeminent pure play in medical devices

Source:      BSC Management estimates. Figures shown assume 2006 full year of combined operation, adjusted for planned Guidant asset divestitures.

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Key Value Drivers: Acquiring Leading Business in High Growth CRM Segment

[CHART]

Source:      Wall Street Research.

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Accelerating Growth

Accelerating Revenue Growth

[CHART]

Note: Low is based on the Boston Scientific Street Case and High is based on the Boston Scientific Management Case

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Accelerating EPS(1) Growth

[CHART]

Note: Low is based on the Boston Scientific Street Case and High is based on the Boston Scientific Management Case. (1) Refer to definition of Adjusted EPS provided in the January 8, 2006 press release.

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DES Pipeline

[CHART]

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US Competitive Advantage

Cypher is trademarks of Cordis Corp.

Endeavor is a trademark of Medtronic, Inc.

ZOMAXX is a trademark of Abbott Laboratories

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Strategic Build Continues

[CHART]

Note: 2006 assumes 1/1/06 acquisition of Guidant; estimated revenue is based on the Boston Scientific Street Case

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Financing the Transaction

Financing the Transaction

(Dollars in billions)

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Post-Closing Debt Maturities

[CHART]

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Cash Available for Debt Repayment

Pro Forma

($ in Billions)

Cumulative Debt Maturities

[CHART]

Cumulative Cash Available for Debt Repayment

[CHART]

Note: Cash flow is based on the Boston Scientific Street Case.

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Roadmap to Completing the Transaction

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ACC Analyst Meeting

March 13^th

7:30 a.m.

Atlanta

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