1. Title of Derivative Security (Instr. 4) |
2. Date Exercisable and Expiration Date (Month/Day/Year) |
3. Title and Amount of Securities Underlying Derivative Security (Instr. 4) |
4. Conversion or Exercise Price of Derivative Security |
5. Ownership Form of Derivative Security: Direct (D) or Indirect (I) (Instr. 5) |
6. Nature of Indirect Beneficial Ownership (Instr. 5) |
Date Exercisable |
Expiration Date |
Title |
Amount or Number of Shares |
Series D Preferred Stock
|
Â
(1)
|
Â
(2)
|
Common Stock
|
1,014,492
(3)
|
$
(4)
|
I
|
Through funds maganged by Reporting Person
(5)
(6)
|
Series E Preferred Stock
|
Â
(1)
|
Â
(2)
|
Common Stock
|
821,153
(7)
|
$
(8)
|
I
|
Through funds maganged by Reporting Person
(5)
(6)
|
* |
If the form is filed by more than one reporting person, see Instruction 5(b)(v). |
** |
Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a). |
(1) |
These securities are exercisable immediately. |
(2) |
These securities do not have an expiration date. |
(3) |
Does not include shares of Common Stock that may be issued if the conditional dividend of shares of Common Stock declared by
the Issuer's Board of Directors on September 8, 2005 is distributed upon the closing of the Issuer's initial public offering
(the "IPO") in the event the price per share of the Issuer's Common Stock sold in the IPO is $11.40 or greater (the
"Conditional Dividend"). |
(4) |
Upon consummation of the IPO, every three shares of Series D Preferred Stock will be converted into one share of Common
Stock. |
(5) |
The Reporting Person is the general partner of TPG Ventures Professionals, L.P., which in turn is the managing member of TPG
Ventures Holdings, L.L.C. ("TPG Holdings"), which is the sole member of each of TPG Ventures Advisors, L.L.C. ("Ventures
Advisors") and TPG Biotech Advisors, L.L.C. ("Biotech Advisors"). Ventures Advisors is the general partner of TPG Ventures
GenPar, L.P., which is the general partner of TPG Ventures, L.P. Biotech Advisors is the general partner of TPG
Biotechnology GenPar, L.P., which is the general partner of TPG Biotechnology Partners, L.P. (together with TPG Ventures
L.P., the "TPG Funds"). TPG Funds directly hold an aggregate of 1,014,492 shares of Series D Preferred Stock and 821,513
shares of Series E Preferred Stock ("the Securities"). |
(6) |
The Reporting Person is deemed to be the beneficial owner of the Securities beneficially owned by the TPG Funds only to the
extent of the greater of its direct or indirect interest in the profits or capital accounts of such funds. Pursuant to Rule
16a-1(a)(4) under the Securities Exchange Act of 1934, as amended (the "Exchange Act"), this filing shall not be deemed an
admission that the Reporting Person is, for purposes of Section 16 of the Exchange Act or otherwise, the beneficial owner of
any securities beneficially owned by the TPG Funds in excess of such amount. The shareholders of the Reporting Person are
David Bonderman, James G. Coulter and William S. Price, III (collectively, the "Shareholders"). However, each Shareholder
disclaims beneficial ownership of any of the Issuer's securities reported herein. |
(7) |
Does not include shares of Common Stock that will be issued upon consummation of the Issuer's IPO as a result of either (a)
the distribution of the Conditional Dividend or (b) the Increased Conversion Rate (as defined in footnote 7 below). |
(8) |
Upon consummation of the IPO, every three shares of Series E Preferred Stock will be converted into one share of Common
Stock; provided, however, if the price per share of Common Stock sold in the IPO is less than $11.40, the conversion rate
will be 1.128 shares of Common Stock for every three shares of Series E Preferred Stock (the "Increased Conversion Rate"). |