PAGE 1
000 A000000 09/30/2011
000 C000000 1258943
000 D000000 N
000 E000000 NF
000 F000000 Y
000 G000000 N
000 H000000 N
000 I000000 6.1
000 J000000 A
001 A000000 PIONEER MUNICIPAL HIGH INCOME ADVANTAGE TRUST
001 B000000 811-21409
001 C000000 6177427825
002 A000000 60 STATE STREET
002 B000000 BOSTON
002 C000000 MA
002 D010000 02109
003 000000 N
004 000000 N
005 000000 N
006 000000 N
007 A000000 N
007 B000000 0
007 C010100 1
008 A000001 PIONEER INVESTMENT MANAGEMENT, INC.
008 B000001 A
008 C000001 801-8255
008 D010001 BOSTON
008 D020001 MA
008 D030001 02109
010 A000001 PIONEER INVESTMENT MANAGEMENT, INC.
010 B000001 801-8255
010 C010001 BOSTON
010 C020001 MA
010 C030001 02109
010 A000002 STATE STREET BANK & TRUST COMPANY
010 C010002 BOSTON
010 C020002 MA
010 C030002 02101
011 A000001 PIONEER FUNDS DISTRIBUTOR, INC.
011 B000001 8-41256
011 C010001 BOSTON
011 C020001 MA
011 C030001 02109
011 C040001 1820
011 A000002 UBS INVESTMENT BANK
011 B000002 8-022651
011 C010002 STAMFORD
011 C020002 CT
011 C030002 06901
011 A000003 RBC CAPITAL MARKETS CORP.
011 B000003 8-045411
PAGE 2
011 C010003 MINNEAPOLIS
011 C020003 MN
011 C030003 55402
011 C040003 4422
011 A000004 MERRILL LYNCH & CO.
011 B000004 8-7221
011 C010004 NEW YORK
011 C020004 NY
011 C030004 10281
011 C040004 1201
011 A000005 JANNEY MONTGOMERY SCOTT, LLC
011 B000005 8-462
011 C010005 PHILADELPHIA
011 C020005 PA
011 C030005 19103
011 C040005 1675
011 A000006 WACHOVIA CAPITAL MARKETS, LLC
011 B000006 8-99999
011 C010006 RICHMOND
011 C020006 VA
011 C030006 23219
012 A000001 PIONEER INVEST. MGMT. SHAREHOLDER SER. INC.
012 B000001 85-01359
012 C010001 BOSTON
012 C020001 MA
012 C030001 02109
012 A000002 AMERICAN STOCK TRANSFER & TRUST CO. (COMMON)
012 B000002 85-00000
012 C010002 BROOKLYN
012 C020002 NY
012 C030002 11219
012 A000003 DEUTSCHE BANK TRUST COMPANY AMERICAS (PREF.)
012 B000003 85-00000
012 C010003 NEW YORK CITY
012 C020003 NY
012 C030003 10005
013 A000001 ERNST & YOUNG, LLP
013 B010001 BOSTON
013 B020001 MA
013 B030001 02116
013 B040001 5072
015 A000001 BROWN BROTHERS HARRIMAN & CO.
015 B000001 C
015 C010001 BOSTON
015 C020001 MA
015 C030001 02109
015 E010001 X
018 000000 Y
019 A000000 Y
019 B000000 55
019 C000000 PIONEERFDS
PAGE 3
021 000000 0
022 A000001 FMSBONDS, INC.
022 B000001 59-1842344
022 C000001 3489
022 D000001 7377
022 A000002 JP MORGAN SECURITIES, INC.
022 B000002 13-3379014
022 C000002 6651
022 D000002 2535
022 A000003 RAYMOND JAMES & ASSOCIATES, INC.
022 B000003 59-1237041
022 C000003 1500
022 D000003 4566
022 A000004 B.C. ZIEGLER AND COMPANY
022 B000004 39-0727640
022 C000004 1971
022 D000004 1553
022 A000005 PIPER JAFFRAY & CO.
022 B000005 41-0953246
022 C000005 2430
022 D000005 868
022 A000006 BANK OF AMERICA CORP
022 B000006 56-0906609
022 C000006 1589
022 D000006 0
022 A000007 JEFFERIES & COMPANY, INC.
022 B000007 95-2622900
022 C000007 1501
022 D000007 0
022 A000008 CAIN BROTHERS & COMPANY, LLC
022 B000008 13-3960078
022 C000008 1500
022 D000008 0
022 A000009 FIRST TRYON SECURITIES LLC
022 B000009 56-1986792
022 C000009 0
022 D000009 1076
022 A000010 BARCLAYS CAPITAL, INC.
022 B000010 61-0316560
022 C000010 1000
022 D000010 0
023 C000000 23900
023 D000000 18511
024 000000 N
026 A000000 N
026 B000000 Y
026 C000000 N
026 D000000 Y
026 E000000 N
026 F000000 N
026 G010000 N
PAGE 4
026 G020000 N
026 H000000 N
027 000000 N
028 A010000 0
028 A020000 0
028 A030000 0
028 A040000 0
028 B010000 0
028 B020000 0
028 B030000 0
028 B040000 0
028 C010000 0
028 C020000 0
028 C030000 0
028 C040000 0
028 D010000 0
028 D020000 0
028 D030000 0
028 D040000 0
028 E010000 0
028 E020000 0
028 E030000 0
028 E040000 0
028 F010000 0
028 F020000 0
028 F030000 0
028 F040000 0
028 G010000 0
028 G020000 0
028 G030000 0
028 G040000 0
028 H000000 0
030 A000000 0
030 B000000 0.00
030 C000000 0.00
031 A000000 0
031 B000000 0
032 000000 0
033 000000 0
035 000000 0
036 B000000 0
038 000000 0
042 A000000 0
042 B000000 0
042 C000000 0
042 D000000 0
042 E000000 0
042 F000000 0
042 G000000 0
042 H000000 0
043 000000 0
PAGE 5
044 000000 0
045 000000 Y
046 000000 N
047 000000 Y
048 000000 0.600
048 A010000 0
048 A020000 0.000
048 B010000 0
048 B020000 0.000
048 C010000 0
048 C020000 0.000
048 D010000 0
048 D020000 0.000
048 E010000 0
048 E020000 0.000
048 F010000 0
048 F020000 0.000
048 G010000 0
048 G020000 0.000
048 H010000 0
048 H020000 0.000
048 I010000 0
048 I020000 0.000
048 J010000 0
048 J020000 0.000
048 K010000 0
048 K020000 0.000
049 000000 N
050 000000 N
051 000000 N
052 000000 N
053 A000000 N
054 A000000 Y
054 B000000 Y
054 C000000 Y
054 D000000 N
054 E000000 N
054 F000000 N
054 G000000 N
054 H000000 Y
054 I000000 N
054 J000000 Y
054 K000000 N
054 L000000 N
054 M000000 Y
054 N000000 N
054 O000000 N
055 A000000 N
055 B000000 N
056 000000 Y
057 000000 N
PAGE 6
058 A000000 N
059 000000 Y
060 A000000 Y
060 B000000 Y
061 000000 0
062 A000000 Y
062 B000000 0.0
062 C000000 0.0
062 D000000 0.0
062 E000000 0.0
062 F000000 0.0
062 G000000 0.0
062 H000000 0.0
062 I000000 0.0
062 J000000 0.0
062 K000000 0.0
062 L000000 0.0
062 M000000 0.0
062 N000000 0.0
062 O000000 146.7
062 P000000 0.0
062 Q000000 0.0
062 R000000 0.3
063 A000000 0
063 B000000 21.3
064 A000000 Y
064 B000000 Y
065 000000 N
066 A000000 N
067 000000 N
068 A000000 N
068 B000000 N
069 000000 N
070 A010000 Y
070 A020000 N
070 B010000 N
070 B020000 N
070 C010000 Y
070 C020000 N
070 D010000 N
070 D020000 N
070 E010000 Y
070 E020000 N
070 F010000 N
070 F020000 N
070 G010000 Y
070 G020000 N
070 H010000 N
070 H020000 N
070 I010000 N
070 I020000 N
PAGE 7
070 J010000 Y
070 J020000 Y
070 K010000 Y
070 K020000 Y
070 L010000 N
070 L020000 N
070 M010000 N
070 M020000 N
070 N010000 N
070 N020000 N
070 O010000 Y
070 O020000 N
070 P010000 Y
070 P020000 N
070 Q010000 N
070 Q020000 N
070 R010000 N
070 R020000 N
071 A000000 25386
071 B000000 26983
071 C000000 424016
071 D000000 6
072 A000000 6
072 B000000 15857
072 C000000 0
072 D000000 0
072 E000000 0
072 F000000 1298
072 G000000 151
072 H000000 0
072 I000000 3
072 J000000 55
072 K000000 0
072 L000000 14
072 M000000 7
072 N000000 12
072 O000000 0
072 P000000 0
072 Q000000 0
072 R000000 31
072 S000000 70
072 T000000 0
072 U000000 0
072 V000000 0
072 W000000 242
072 X000000 1883
072 Y000000 0
072 Z000000 13974
072AA000000 2102
072BB000000 0
072CC010000 25702
PAGE 8
072CC020000 0
072DD010000 13088
072DD020000 0
072EE000000 0
073 A010000 0.5700
073 A020000 0.0000
073 B000000 0.0000
073 C000000 0.0000
074 A000000 3678
074 B000000 0
074 C000000 0
074 D000000 434521
074 E000000 0
074 F000000 831
074 G000000 0
074 H000000 0
074 I000000 0
074 J000000 90
074 K000000 0
074 L000000 9488
074 M000000 49
074 N000000 448657
074 O000000 0
074 P000000 301
074 Q000000 0
074 R010000 0
074 R020000 0
074 R030000 0
074 R040000 2126
074 S000000 150005
074 T000000 296225
074 U010000 23204
074 U020000 0
074 V010000 12.77
074 V020000 0.00
074 W000000 0.0000
074 X000000 9231
074 Y000000 0
075 A000000 0
075 B000000 282000
076 000000 13.85
077 A000000 N
078 000000 N
080 C000000 0
081 B000000 0
082 B000000 0
083 B000000 0
084 B000000 0
086 A010000 70
086 A020000 895
086 B010000 0
PAGE 9
086 B020000 0
086 C010000 0
086 C020000 0
086 D010000 0
086 D020000 0
086 E010000 0
086 E020000 0
086 F010000 0
086 F020000 0
087 A010000 COMMON STOCK
087 A020000 723762100
087 A030000 MAV
087 B010000 PREFERRED STOCK - SERIES A
087 B020000 723762209
087 C010000 PREFERRED STOCK - SERIES B
087 C020000 723762308
088 A000000 N
088 B000000 N
088 C000000 N
088 D000000 Y
SIGNATURE MARK E. BRADLEY
TITLE TREASURER