Ownership Submission
FORM 3
 UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

INITIAL STATEMENT OF BENEFICIAL OWNERSHIP OF SECURITIES

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934, Section 17(a) of the Public Utility Holding Company Act of 1935 or Section 30(h) of the Investment Company Act of 1940
OMB APPROVAL
OMB Number: 3235-0104
Expires: January 31, 2005
Estimated average burden hours per response... 0.5

(Print or Type Responses)
1. Name and Address of Reporting Person *
  BEIER DAVID W
 2. Date of Event Requiring Statement (Month/Day/Year)
03/11/2008		 3. Issuer Name and Ticker or Trading Symbol
AMGEN INC [AMGN]
(Last)
(First)
(Middle)
ONE AMGEN CENTER DRIVE		 4. Relationship of Reporting Person(s) to Issuer
(Check all applicable)
_____ Director _____ 10% Owner
__X__ Officer (give title below) _____ Other (specify below)
SVP Global Govt & Corp Affairs
 5. If Amendment, Date Original Filed(Month/Day/Year)
(Street)

THOUSAND OAKS, CA 91320-1799		 6. Individual or Joint/Group Filing(Check Applicable Line)
_X_ Form filed by One Reporting Person
___ Form filed by More than One Reporting Person
(City)
(State)
(Zip)
Table I - Non-Derivative Securities Beneficially Owned
1.Title of Security
(Instr. 4)		 2. Amount of Securities Beneficially Owned
(Instr. 4)		 3. Ownership Form: Direct (D) or Indirect (I)
(Instr. 5)		 4. Nature of Indirect Beneficial Ownership
(Instr. 5)
Common Stock 25,000 (1)
D
 
Common Stock 15,824
D
 

Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly. SEC 1473 (7-02)
Persons who respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB control number.

Table II - Derivative Securities Beneficially Owned (e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security
(Instr. 4)		 2. Date Exercisable and Expiration Date
(Month/Day/Year)		 3. Title and Amount of Securities Underlying Derivative Security
(Instr. 4)		 4. Conversion or Exercise Price of Derivative Security 5. Ownership Form of Derivative Security: Direct (D) or Indirect (I)
(Instr. 5)		 6. Nature of Indirect Beneficial Ownership
(Instr. 5)
Date Exercisable Expiration Date Title Amount or Number of Shares
ISO (Right to Buy) 03/15/2008(2) 03/15/2011 Common Stock 3,362 $ 59.48 D  
ISO (Right to Buy) 12/17/2004 12/17/2010 Common Stock 6,436 $ 62.15 D  
ISO (Right to Buy) 04/26/2011 04/26/2014 Common Stock 1,598 $ 62.55 D  
ISO (Right to Buy) 04/03/2010 04/03/2013 Common Stock 1,391 $ 71.88 D  
NQSO (Right to Buy) 03/15/2006(3) 03/15/2012 Common Stock 17,500 $ 58.61 D  
NQSO (Right to Buy) 03/15/2005(4) 03/15/2011 Common Stock 6,336 $ 59.48 D  
NQSO (Right to Buy) 12/17/2004(5) 12/17/2010 Common Stock 40,732 $ 62.15 D  
NQSO (Right to Buy) 04/26/2008(6) 04/26/2014 Common Stock 23,402 $ 62.55 D  
NQSO (Right to Buy) 04/03/2007(7) 04/03/2013 Common Stock 23,609 $ 71.88 D  

Reporting Owners

Reporting Owner Name / Address Relationships
Director 10% Owner Officer Other
BEIER DAVID W
ONE AMGEN CENTER DRIVE
THOUSAND OAKS, CA 91320-1799		       SVP Global Govt & Corp Affairs  

Signatures

/s/ David W. Beier 03/18/2008
**Signature of Reporting Person Date

Explanation of Responses:

* If the form is filed by more than one reporting person, see Instruction 5(b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
(1) The Restricted Stock Units (RSUs) were granted under the Company's Amended and Restated 1991 Equity Incentive Plan. RSUs will fully vest on July 31, 2010. Vested RSUs will be paid in shares of the Company's common stock on a one-to-one basis unless payment is otherwise deferred by the reporting person.
(2) This option is exercisable in two equal annual installments of 1,681 shares each commencing March 15, 2008.
(3) This option is exercisable in four equal annual installments of 4,375 shares each commencing March 15, 2006.
(4) This option is exercisable in five annual installments as follows: 3,168 shares on March 15, 2005; 3,168 shares on March 15, 2006; 3,168 shares on March 15, 2007; 1,487 shares on March 15, 2008; and 1,487 shares on March 15, 2009.
(5) This option was exercisable in four equal annual installments commencing December 17, 2004 and is now fully vested.
(6) This option is exercisable in four annual installments as follows: 6,250 shares on April 26, 2008; 6,250 shares on April 26, 2009; 6,250 shares on April 26, 2010; and 4,652 shares on April 26, 2011.
(7) This option is exercisable in four annual installments as follows: 6,250 shares on April 3, 2007; 6,250 shares on April 3, 2008; 6,250 shares on April 3, 2009; and 4,859 shares on April 3, 2010.

Note: File three copies of this Form, one of which must be manually signed. If space is insufficient, See Instruction 6 for procedure.

Potential persons who are to respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB number.