UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 SCHEDULE 13D UNDER THE SECURITIES EXCHANGE ACT OF 1934 (AMENDMENT NO. 3) ANORMED, INC. -------------------------------------------------------------------------------- (Name of Issuer) COMMON STOCK, NO PAR VALUE PER SHARE -------------------------------------------------------------------------------- (Title of Class of Securities) 035910108 -------------------------------------------------------------------------------- (CUSIP Number) LEO KIRBY 667 MADISON AVENUE, 19TH FLOOR NEW YORK, NY 10021 (212) 521-2418 -------------------------------------------------------------------------------- (Name, Address and Telephone Number of Person Authorized to Receive Notices and Communications) JANUARY 24, 2006 -------------------------------------------------------------------------------- (Date of Event which Requires Filing of this Statement) If the filing person has previously filed a statement on Schedule 13G to report the acquisition that is the subject of this Schedule 13D, and is filing this schedule because of Rule 13d-1(e), 13d-1(f) or 13d-1(g), check the following box. |_| NOTE: Schedules filed in paper format shall include a signed original and five copies of the schedule, including all exhibits. See Rule 13d-7 for other parties to whom copies are to be sent. *The remainder of this cover page shall be filled out for a reporting person's initial filing on this form with respect to the subject class of securities, and for any subsequent amendment containing information which would alter disclosures provided in a prior cover page. The information required on the remainder of this cover page shall not be deemed to be "filed" for the purpose of Section 18 of the Securities Exchange Act of 1934 (the "Act") or otherwise subject to the liabilities of that section of the Act but shall be subject to all other provisions of the Act (however, see the Notes). Page 1 of 7 Pages SCHEDULE 13D ----------------------------------------- -------------------------------- CUSIP NO. 035910108 PAGE 2 OF 6 PAGES ----------------------------------------- -------------------------------- ---------------------------------------------------------------------------------------------------------------------- 1 NAMES OF REPORTING PERSONS I.R.S. IDENTIFICATION NOS. OF ABOVE PERSONS Julian C. Baker ---------------------------------------------------------------------------------------------------------------------- 2 CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP (See Instructions) (A) |X| (B) |_| ---------------------------------------------------------------------------------------------------------------------- 3 SEC USE ONLY ---------------------------------------------------------------------------------------------------------------------- SOURCE OF FUNDS (See Instructions) 4 WC ---------------------------------------------------------------------------------------------------------------------- 5 CHECK BOX IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED PURSUANT TO ITEMS 2(d) OR 2(e) |_| ---------------------------------------------------------------------------------------------------------------------- 6 CITIZENSHIP OR PLACE OF ORGANIZATION United States ---------------------------------------------------------------------------------------------------------------------- NUMBER OF 7 SOLE VOTING POWER SHARES BENEFICIALLY 0 OWNED BY ------------------------------------------------------------------------------------------ EACH 8 SHARED VOTING POWER REPORTING PERSON 9,411,500 WITH ------------------------------------------------------------------------------------------ 9 SOLE DISPOSITIVE POWER 0 ---------------------------------------------------------------------------------------------------------------------- 10 SHARED DISPOSITIVE POWER 9,411,500 ---------------------------------------------------------------------------------------------------------------------- 11 AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON 9,411,500 ---------------------------------------------------------------------------------------------------------------------- 12 CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (11) EXCLUDES CERTAIN SHARES |_| (See Instructions) ---------------------------------------------------------------------------------------------------------------------- 13 PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11) 23.3% ---------------------------------------------------------------------------------------------------------------------- 14 TYPE OF REPORTING PERSON (See Instructions) IN ---------------------------------------------------------------------------------------------------------------------- SCHEDULE 13D ----------------------------------------- -------------------------------- CUSIP NO. 035910108 PAGE 3 OF 6 PAGES ----------------------------------------- -------------------------------- ---------------------------------------------------------------------------------------------------------------------- 1 NAMES OF REPORTING PERSONS I.R.S. IDENTIFICATION NOS. OF ABOVE PERSONS Felix J. Baker ---------------------------------------------------------------------------------------------------------------------- 2 CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP (See Instructions) (A) |X| (B) |_| ---------------------------------------------------------------------------------------------------------------------- 3 SEC USE ONLY ---------------------------------------------------------------------------------------------------------------------- SOURCE OF FUNDS (See Instructions) 4 WC ---------------------------------------------------------------------------------------------------------------------- 5 CHECK BOX IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED PURSUANT TO ITEMS 2(d) OR 2(e) |_| ---------------------------------------------------------------------------------------------------------------------- 6 CITIZENSHIP OR PLACE OF ORGANIZATION United States ---------------------------------------------------------------------------------------------------------------------- NUMBER OF 7 SOLE VOTING POWER SHARES BENEFICIALLY 25,000 OWNED BY ------------------------------------------------------------------------------------------ EACH 8 SHARED VOTING POWER REPORTING PERSON 9,411,500 WITH ---------------------------------------------------------------------------------------------------------------------- 9 SOLE DISPOSITIVE POWER 25,000 ---------------------------------------------------------------------------------------------------------------------- SHARED DISPOSITIVE POWER 10 9,411,500 ---------------------------------------------------------------------------------------------------------------------- 11 AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON 9,436,500 ---------------------------------------------------------------------------------------------------------------------- 12 CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (11) EXCLUDES CERTAIN SHARES |_| (See Instructions) ---------------------------------------------------------------------------------------------------------------------- 13 PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11) 23.3% ---------------------------------------------------------------------------------------------------------------------- TYPE OF REPORTING PERSON (See Instructions) 14 IN ---------------------------------------------------------------------------------------------------------------------- This Amendment No. 3 to Schedule 13D is being filed by Julian C. Baker and Felix J. Baker (the "Reporting Persons") to supplement the statements on Schedule 13D previously filed by them, as heretofore amended. Except as supplemented herein, such statements, as heretofore amended and supplemented, remain in full force and effect. ITEM 4. PURPOSE OF TRANSACTION. Following the filing by the Reporting Persons of their Amendment No. 2 to their statement on Schedule 13D, the Reporting Persons were informed that a special committee has been formed, consisting of all directors except for Felix Baker and Michael Abrams, to evaluate and respond to the Reporting Persons' proposal to change the composition of the board of directors of the Company. The Reporting Persons have recommended that the following persons be elected to the board of directors of the Company. Felix Baker, Ph.D. Managing Partner Baker Brothers Investments 667 Madison Ave, 17th floor New York, NY 10021 US citizen Joseph P. Dougherty, Ph.D. Managing Director Seaview Securities LLC 117 E. 55th St. New York, NY, 10022 US citizen Henry J. Fuchs, MD Executive Vice President and Chief Medical Officer Onyx Pharmaceuticals 2100 Powell Street Emeryville, CA 94608 US citizen Kenneth Galbraith Gigha Consulting # 800 -15355 24th Avenue White Rock, BC V4A 2H9 Canadian citizen Jacques Lapointe Chairman of ConjuChem, Inc. P.O. Box 398 7774 Tenth Sideroad Milton, Ontario L9T 4Y9 Canadian citizen Page 4 of 7 Pages Berl Nadler Davies Ward Phillips & Vineberg LLP 44th Floor 1 First Canadian Place Toronto, Ontario M5X 1B1 Canadian citizen Kelvin Neu, MD Associate Baker Brothers Investments 667 Madison Ave, 17th floor New York, NY 10021 Singapore citizen The Reporting Persons intend to continue to evaluate their alternatives as circumstances develop. ITEM 7. MATERIAL TO BE FILED AS EXHIBITS. Exhibit 1 Agreement regarding the joint filing of this statement. Page 5 of 7 Pages SIGNATURE After reasonable inquiry and to the best of my knowledge and belief, I certify that the information set forth in this statement is true, complete and correct. January 26, 2006 By: /s/ Julian C. Baker ----------------------------------- Julian C. Baker By: /s/ Felix J. Baker ------------------------------------ Felix J. Baker Page 6 of 7 Pages